Sirtuins: Enzymes with multidirectional catalytic activity
نویسندگان
چکیده
منابع مشابه
Phosphorylation Modulates Catalytic Activity of Mycobacterial Sirtuins
Sirtuins are NAD(+)-dependent deacetylases involved in the regulation of diverse cellular processes and are conserved throughout phylogeny. Here we report about in vitro transphosphorylation of the only NAD(+)-dependent deacetylase (mDAC) present in the genome of Mycobacterium tuberculosis by eukaryotic-type Ser/Thr kinases, particularly PknA. The phosphorylated mDAC displayed decreased deacety...
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ژورنال
عنوان ژورنال: Postępy Higieny i Medycyny Doświadczalnej
سال: 2021
ISSN: 0032-5449,1732-2693
DOI: 10.5604/01.3001.0014.7866